jmcfar_98 said:

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Absolute said:

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Think I'm going to take a couple weeks off the Reta. Been having pretty bothersome stomach issues this week. Really bad reflux at night last couple nights. Plus just a general feeling of GI yuckiness.

Will give it a break then try some more. Any ideas on better managing that type of thing?

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What's the dosage amount and are you doing weekly injections or a couple per week. A lot of folks have been splitting them into two or three shots per week to help with the GI issues.

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I have been splitting it up. .5 every third day. Start early February and had some minor issues, but it was bearable and not too bad.


I know I am predisposed to the issue of the reflux. Reta has actually been easier to deal with than when I tried ozempic several years ago. Have had very little issue overall. Just the last week or so been feeling off and what was occasional reflux, has gotten worse and more frequent.

I'm ok with taking a break and then starting back up. Have seen good results.

thanks for the rec for tesa. About to incorporate MOT-C with my Reta campaign. Any experience or recommendations on MOT-C?

I've been on TRT since 2023, and felt CJC/IPA added another level of energy to the TRT.

I initially purchased 4 vials of 5/5 mg that lasted me 4-5 weeks, and actually just used up the last vial last night. I'll update in the next few weeks if I see energy decrease.

I would suggest injecting maybe an hour before going to bed. I usually inject around 9pm and go to sleep at 10p without issues. But I can understand not being able to sleep given the flush, sting, etc.

this will sound silly, but try Tums Chewy Bites for heartburn relief. I saw this in my reels feed once and it has helped me. Sometimes I wake up in the night with bad burn, I'll pop one of these and by the time I get back in bed it's subsided.

Run SS-31 first for 21 days or run it along with Motsc and alternate. SS31 Monday Thursday and Motsc Tuesday Friday.

It's a good protocol to do, but you may or may not "feel" anything. Some people with jacked up mitochondria respond really well, but if you're in decent shape you may not notice much, but it's good to run at least once a year.

I did ss31 and Motsc on my first cycle this year and now am running Humanin for the mito portion of my peptide cycle.

Brand new to this, was hoping for a little guidance. 45 year old male, looking to lose fat/build muscle. Summarized this thread via Gemini and was going to start Tesamorelin and a IPA/CJC Blend.

Wasn't sure about dosing, any suggestions?

I would highly encourage you to read through the thread. There is tons of good info, websites and anecdotes that ai can't capture. AI and Reddit get so much crap wrong in the peptide space.

Plus it's your health, and you're looking for a change, so educating yourself is the best first step. Congrats!

I wouldn't waste my time with cjc, just do ipamorelin and tesamorelin.

Assuming you are eating right and lifting, get your testosterone optimized, use Retatrutide and HGH, and support that with peptide cycles.

agree with MosesHallEnforcer, take some time to read the thread because there are several options. However, I would suggest a baseline of Reta for weight loss and Ipamorelin and/or Tesamorelin for muscle building.

Keep in mind these are supplements, not miracle products. You need your diet and macros dialed in, as well as incorporating exercise/activities/weightlifting.

Also check out peptidedosages.com for protocols.

Appreciate the responses. Workout regularly and eat well, and am pretty fit, not trying to lose weight, just want more muscle/less fat, feel a bit better, etc.

Will go through the thread, thanks again!

I don't know if it has anything to do with the flush/sting. More so to do with just general restlessness after I inject.

I was also taking it an hour or so before bed fasted. Might try to take it in the morning and see how that goes.

I've actually started KPV for gut/reflux issues. So far so good. For reference I'm also on Reta and Ghk-cu

Sounds like you have it dialed in and just need a boost. Definitely try Reta for fat loss and IPA and/or Tesa for muscle build. Have you checked your testosterone? TRT was a gamechanger for me.

tam2002 said:

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I've actually started KPV for gut/reflux issues. So far so good. For reference I'm also on Reta and Ghk-cu

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Saw your post about it. Actually sourced somebody haven't purchased yet. Got busy and forgot.

Have you noticed it working?

I'm only a week in so I admit it's probably not been long enough to really work but fwiw I haven't had much if any acid reflux or burping up from my belly like I have been

Had testosterone checked a few years ago, was normal. Planning on starting what I had posted above to see how it works and go from there. Thanks!

Coates said:

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Had testosterone checked a few years ago, was normal. Planning on starting what I had posted above to see how it works and go from there. Thanks!

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Not sure exactly which post you're referring to, but if you're going to run GH secretagogues, you need to pair one of tesamorelin or CJC with your ipamorelin, not both. CJC and tesa are both GHRH peptides and act on the same receptors and pathways, so you don't need that redundancy.

Ipamorelin is a GHRP, so it's synergistic with a GHRH.


Edit to add... You can do it as you wish, of course, but I think most would recommend only one GHRH in your stack.

Finished up my 12-week cycle of Tesamorelin this week. Goal was to get rid of visceral fat.

Feb DEXA scan (4 weeks into cycle): 201cm^2 visceral fat
Today's DEXA scan (post-cycle): 136cm^2 visceral fat

Is it still too high? Yes. But am I enormously happy with a 33% decrease in only 8 weeks? Also yes. It actually beat the clinical testing data for Tesamorelin (15-18% reduction in 26 weeks).

DEXA was also good as a calibration for my Withings body scan scale, which is consistently 2-4% higher than the DEXA scan for body fat, and it underestimated the difference in my visceral fat.

Granted, the GH element of Tesa spiked my insulin resistance numbers, as mentioned above, but I'll get some more bloods done in 6-8 weeks and hopefully that'll all normalise a bit.

Hey congratulations, that so awesome to hear! Can't wait to hear about the next victories!

Have read all 14 pages. Where is your favorite place to go for more research?

I started sermorelin about three weeks ago but due to the advice of this thread just placed an order for ipamorelin and tesamorelin with bac water. We will see how that goes. Also on TRT treatments.

Nice. Since you've already got the TRT down, you'll probably see good results from the tesa/ipa combo.

What's your goal with it? And did you get separate vials or a pre-combined stack?

AgEng06 said:

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Nice. Since you've already got the TRT down, you'll probably see good results from the tesa/ipa combo.

What's your goal with it? And did you get separate vials or a pre-combined stack?

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The goal is to get shredded. And I got separate vials to start. I'm very new to peptides as I found about their existence just a month ago.

From suggestions from friends after I reconstitute the vials with 2ml of bac water then it's 20 units of tesa and 10 units of ipa nightly. I have a two month supply so will do that and re-evaluate at the end.

That sounds good.

Based on that info, I'm assuming those are 10mg vials and you're dosing 1mg tesa and 0.5mg ipa per day. I had good results with visceral/belly fat using the same combo (at 1mg/0.33mg dosages).

However, if you don't quite get the level of shred you want from those, retatrutide is your next lever you can pull and it will definitely get you there.

CoolaidWade said:

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AgEng06 said:

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Nice. Since you've already got the TRT down, you'll probably see good results from the tesa/ipa combo.

What's your goal with it? And did you get separate vials or a pre-combined stack?

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The goal is to get shredded. And I got separate vials to start. I'm very new to peptides as I found about their existence just a month ago.

From suggestions from friends after I reconstitute the vials with 2ml of bac water then it's 20 units of tesa and 10 units of ipa nightly. I have a two month supply so will do that and re-evaluate at the end.

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Why did you opt for separate vs a blend? Just curious.

I did that and for some reason the tesa is now a gel, not sure if there's anything I can do to save it? First go at this and I already screwed it up.

How much BAC water did you add?

Usually if it's completely gelled it's done for.

AgEng06 said:

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How much BAC water did you add?

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2 ml

I am on week 3 of taking CJC/IPA and am really starting to see results in the fat/muscle category. I feel like after I inject in the morning my muscles tighten up a hair and I feel much more athletic. Down almost 10 pounds overall, gained some muscle mass, lost fat and feel great.

After this 6 weeks is up I am considering dropping the CJC and going straight Tesa/Ipa. Anyone here have any thoughts on that?

Coates said:

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AgEng06 said:

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How much BAC water did you add?

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2 ml

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Sorry for the delayed response... That should be good then. I have heard/read that tesa can gel up if you don't use enough BAC water and that adding more can help, but that shouldn't be the issue here.

Maximus Johnson said:

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I am on week 3 of taking CJC/IPA and am really starting to see results in the fat/muscle category. I feel like after I inject in the morning my muscles tighten up a hair and I feel much more athletic. Down almost 10 pounds overall, gained some muscle mass, lost fat and feel great.

After this 6 weeks is up I am considering dropping the CJC and going straight Tesa/Ipa. Anyone here have any thoughts on that?

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Just my semi-informed opinion.... I think that would probably do well. As you may know, CJC and tesa are the same kind of secretagogues (GHRH) so they act on the same receptors, and are usually run on 8-week cycles (but can be extended if desired). However, since you're 6 weeks in, it would probably be ok to switch to tesa/ipa and run it for 2-6 more weeks (8-12 weeks total). But then I would cycle off and use something else for 8 weeks or so.

How long do I need to be off before I get back on? What would you recommend I take in the interim? I am also taking NAD+ now with the CJC/IPA.

I would probably cycle off for at least 4 weeks, but others may be able to give you more info on that.

In the meantime, if your goal is to continue fat loss, retatrutide or tirzepatide is going to be the best thing you can do.

Other things could include 5-Amino-1MQ, MOTS-c, and the NAD+ you are currently taking. Also MK-677 or MK-777, although they aren't technically peptides, they still act as a GH secretagogue and ghrelin receptor agonist. MK-677 is the "older" version that is well-studied, while MK-777 is the newer version with less studies around it (but I've seen lots of positive feedback) and supposedly less side effects.

And, as always, the baseline for all of this is hormone optimization (testosterone and HGH, if you're into that). Having those hormones in order will definitely improve the results you see from the peptides.

AgEng06 said:

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Coates said:

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AgEng06 said:

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How much BAC water did you add?

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2 ml

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Sorry for the delayed response... That should be good then. I have heard/read that tesa can gel up if you don't use enough BAC water and that adding more can help, but that shouldn't be the issue here.

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No worries, I tried to add more but nothing changed.

Where do you buy your peptides and Reta?

Yeah, that vial is probably a goner then.

There are online vendors listed in this thread (and a few others) - BioLongevity Labs, Soma Chems, Parabolic Peptides, and Profound Aminos. BioLongevity Labs is probably the most expensive of those 3, but there's almost always a sale going on for different compounds. They also accept credit cards, if that matters to you. I haven't ordered from Profound, but Soma and Parabolic don't take CCs.

If you go to the BioLongevity site and subscribe to the emails, you'll know about the sales, but Jay Campbell (one of the owners) will also spam the hell out of you with multiple emails a day. You have been warned haha

AgEng06 said:

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Yeah, that vial is probably a goner then.

There are online vendors listed in this thread (and a few others) - BioLongevity Labs, Soma Chems, Parabolic Peptides, and Profound Aminos. BioLongevity Labs is probably the most expensive of those 3, but there's almost always a sale going on for different compounds. They also accept credit cards, if that matters to you. I haven't ordered from Profound, but Soma and Parabolic don't take CCs.

If you go to the BioLongevity site and subscribe to the emails, you'll know about the sales, but Jay Campbell (one of the owners) will also spam the hell out of you with multiple emails a day. You have been warned haha

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Thanks, I am on Jay's email list and you are correct!

I may be looking wrong, but I don't see reta on biolongevity